5,5′-[Methylenebis(sulfanediyl)]bis(1,3,4-thiadiazol-2-amine)

Synthesis and Antimicrobial Evaluation of 5-(p-substituted phenyl)-N-(3-(5-nitrofur-2-yl) allylidene)-1,3,4-thiadiazol-2-amine Derivatives

5-(p-Substituted phenyl)-N-(3-(5-nitrofur-2-yl)allylidene)-1,3,4-thiadiazol-2-amines 10-17 were prepared utilizing different p-substituted benzoic acid through two step reactions. Firstly, thiosemicarbzide was reacted with benzoic acid derivatives 1 in the presence of phosphorus oxychloride to give 2amino-5-substituted-1,3,4-thiadiazoles 2-9. These compounds were reacted with 5-nitro-2-furanacr...

Application Note 55 AN 55 - 2 TUBE CURRENT

3-Benzyl­oxypyridin-2-amine

In the title compound, C(12)H(12)N(2)O, the dihedral angle between the planes of the pyridine and phenyl rings plane is 35.94 (12)°. In the crystal structure, centrosymmetrically related mol-ecules are linked by a pair of N-H⋯N hydrogen bonds, forming a dimer with an R(2) (2)(8) ring motif. In addition, there is an intra-molecular N-H⋯O inter-action.

6-Methyl­pyridin-2-amine

In the title mol-ecule, C6H8N2, the endocyclic angles are in the range 118.43 (9)-122.65 (10)°. The mol-ecular skeleton is planar (r.m.s. deviation = 0.007 Å). One of the two amino H atoms is involved in an N-H⋯N hydrogen bond, forming an inversion dimer, while the other amino H atom participates in N-H⋯π inter-actions between the dimers, forming layers parallel to (100).

4-Ethoxy­pyridin-2-amine

The title compound, C(7)H(10)N(2)O, crystallizes with two independent mol-ecules in the asymmetric unit. The bond lengths and angles in the mol-ecules are within normal ranges. The crystal structure is stabilized by inter-molecular N-H⋯N hydrogen bonds, linking the two independent mol-ecules into hydrogen-bonded dimers.